Involvement of a membrane potassium channel in heparan sulphate-induced activation of macrophages
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چکیده
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effect of sub-grid scales on large eddy simulation of particle deposition in a turbulent channel flow
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15 صفحه اولNew insights into endotoxin-induced activation of macrophages: involvement of a K+ channel in transmembrane signaling.
LPS (endotoxins) activate cells of the human immune system, among which are monocytes and macrophages, to produce endogenous mediators. These regulate the immune response, but may also cause severe harm leading to septic shock. The activation of monocytes/macrophages by LPS is mediated by a membrane-bound LPS receptor, mCD14. As mCD14 lacks a transmembrane domain, a further protein is required ...
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The morphological changes that occur during intestinal development have been extensively described, but the molecular basis of these changes is largely unknown. As a result of our efforts to identify molecules that play a role in intestinal morphogenesis during development, we have previously isolated a cDNA that is developmentally regulated in the intestine. This cDNA, named OCI-5, was recentl...
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15 صفحه اولAn evidence for a potassium channel in endoplasmic reticulum based on single channel recording in bilayer lipid membrane
Introduction Numerous studies have demonstrated the presence of potassium selective channels in membranes internal organelles. These channels are essential to a large variety of cellular processes including intracellular 2+ a signaling, protein recycling, charge neutralization and cell protection. In contrast to the sarcoplasmic reticulum + here potassium channels have been clearly ...
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ژورنال
عنوان ژورنال: Immunology
سال: 2014
ISSN: 0019-2805
DOI: 10.1111/imm.12193